Return to our Home Page


Technical Resources
Technical Information
Calbiochem Information
Interactive Pathways
Checkpoint Signaling & DNA Repair
Checkpoint Signaling and DNA Repair: CHK1
 
CHK1 Antibodies
 
CHK1 Inhibitors
 
CHK1 Kit
 
CHK1 Proteins
 
Additional Information
 
 
 
 

Protein : Chk1

SwissProt Accessions | Entrez Gene links

Connectivity 250
Hugo ID 1925
Name Chk1
Description checkpoint kinase 1 homolog (S. pombe)
URN urn:agi-llid:1111

GO Cellular Component nucleus
condensed nuclear chromosome

Cell Localization Cytoplasm
Nucleus

GO Biological Process DNA damage checkpoint
G2/M transition of mitotic cell cycle
cell cycle
protein amino acid phosphorylation
response to DNA damage stimulus
gametogenesis
meiotic recombination
negative regulation of cell proliferation
regulation of cyclin dependent protein kinase activity

EC Number 2.7.1.37

MGI ID 1202065

Swiss-Prot Accession  O14757

OMIM ID OMIM:603078

Alias Chek1
checkpoint kinase 1 homolog (S. pombe)
Chk1
rad27
rad27 homolog (S.pombe)
C85740
expressed sequence C85740
CHK1 checkpoint homolog (S. pombe)
Chk1 protein kinase
CHK1_HUMAN
checkpoint kinase 1 homolog
Checkpoint, S. pombe, homolog of, I
Chek I
CHK I
CHK1 checkpoint homolog
homolog of S. pombe Checkpoint, 1
homolog of S. pombe Checkpoint, I
Serine/threonine-protein kinase Chk I
Serine/threonine-protein kinase Chk1
homolog (S.pombe)

Organism Rattus norvegicus
Mus musculus
Human

Entrez ID  140583
12649
97555
1111

RGD ID 620545

Pathway RB Tumor Suppressor
ATM signaling
DNA Repair
'GSK3 50' plus

Unigene ID Rn.33267
Mm.16753
Hs.24529

Group Kinases
nucleotide binding