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Checkpoint Signaling and DNA Repair: HDAC1
 | | |  HDAC1 Antibodies
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| Anti-Histone Deacetylase 1 (467-482) Rabbit pAb |
IB, IF |
canine, hamster, human, mouse, rat |
PC544 |
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| | | | Additional Information | | | | | | | | |
| Protein : HDAC1
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| Connectivity | 472 |
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| Notes | Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. |
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| Hugo ID | 4852 |
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| Name | HDAC1 |
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| Description | histone deacetylase 1 |
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| URN | urn:agi-llid:3065 |
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| GO Cellular Component | NuRD complex |
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| | heterochromatin |
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| | histone deacetylase complex |
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| | nucleus |
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| | cytoplasm |
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| Cell Localization | Cytoplasm |
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| | Nucleus |
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| GO Biological Process | chromatin modification |
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| | endoderm development |
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| | regulation of transcription, DNA-dependent |
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| | anti-apoptosis |
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| | histone deacetylation |
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| Alias | Hdac1 |
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| | histone deacetylase 1 |
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| | HD1 |
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| | RPD3 |
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| | RPD3L1 |
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| | HDA1 |
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| | reduced potassium dependency, yeast homolog-like 1 |
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| | HDA1_HUMAN |
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| | HDAC I |
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| | histone deacetylase I |
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| | reduced potassium dependency, yeast homolog-like I |
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| | RPD3L I |
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| | similar to histone deacetylase |
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| | similar to histone deacetylase (Takifugu rubripes) |
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| | similar to histone deacetylase 1 |
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| | similar to histone deacetylase I |
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| | similar to histone deaceytlase 1 |
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| | similar to histone deaceytlase I |
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| | similar to putative histone deacetylase |
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| | similar to RPD3 protein |
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| | reduced potassium dependency, homolog-like 1 |
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| | reduced potassium dependency, yeast homolog-like |
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| | HD I |
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| Organism | Rattus norvegicus |
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| | Mus musculus |
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| | Human |
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| Pathway | imported DNA Repair proteins |
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