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Checkpoint Signaling and DNA Repair: WEE1
 | | | Inhibitor
| | | Enzyme
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| Wee1, GST-Fusion, Human, Recombinant, S. frugiperda |
325896 |
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| | | | Additional Information | | | | | | | | |
| Protein : WEE1
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| Connectivity | 102 |
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| Notes | This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. |
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| Hugo ID | 12761 |
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| Name | WEE1 |
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| Description | wee 1 homolog (S. pombe) |
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| URN | urn:agi-llid:7465 |
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| GO Cellular Component | nucleus |
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| Cell Localization | Nucleus |
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| GO Biological Process | mitosis |
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| | protein amino acid phosphorylation |
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| | regulation of cell cycle |
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| Alias | Wee1 |
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| | wee 1 homolog (S. pombe) |
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| | WEE1hu |
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| | WEE1 homolog (S. pombe) |
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| | WEE1+ homolog (S. pombe) |
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| | wee1+ (S. pombe) homolog |
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| | wee1-like protein kinase |
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| | wee1 tyrosine kinase |
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| | similar to Wee1-like protein kinase |
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| | wee 1 homolog |
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| | WEE I |
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| Organism | Mus musculus |
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| | Human |
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| Pathway | RB Tumor Suppressor |
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| | DNA Repair |
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| Group | Kinases |
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| | nucleotide binding |
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