 |
|
|
|
|
Checkpoint Signaling and DNA Repair: gH2AX
 | | |  gH2AX Antibodies
|
|
|
|
|
| PhosphoDetect™ Anti-H2AX (pSer139) Rabbit pAb |
IB, IC |
human, mouse |
DR1017 |
| Anti-H2AX Rabbit pAb |
IB, IP |
human, mouse |
DR1016 |
|
| | | | Additional Information | | | | | | | | |
| Protein : gammaH2AX
| | |
|---|
| Connectivity | 69 |
|---|
| Notes | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. |
|---|
| Hugo ID | 4739 |
|---|
| Name | gammaH2AX |
|---|
| Description | H2A histone family, member X |
|---|
| URN | urn:agi-llid:3014 |
|---|
| | |
|---|
| GO Cellular Component | chromatin |
|---|
| | chromosome |
|---|
| | nucleosome |
|---|
| | nucleus |
|---|
| | |
|---|
| Cell Localization | Nucleus |
|---|
| | |
|---|
| GO Biological Process | DNA repair |
|---|
| | NOT DNA damage checkpoint |
|---|
| | chromosome organization and biogenesis (sensu Eukarya) |
|---|
| | double-strand break repair via homologous recombination |
|---|
| | nucleosome assembly |
|---|
| | spermatogenesis |
|---|
| | |
|---|
| Alias | Dpagt1 |
|---|
| | dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) |
|---|
| | H2afx |
|---|
| | H2ax |
|---|
| | H2A.X |
|---|
| | H2A histone family, member X |
|---|
| | histone 5 protein 2ax |
|---|
| | Hist5-2ax |
|---|
| | H2A/X |
|---|
| | H2AX histone |
|---|
| | P-H2AX |
|---|
| | Histone H2A.x |
|---|
| | similar to Histone H2A.x (H2a/x) |
|---|
| | H2-AX |
|---|
| | H(2)AX |
|---|
| | H 2AX |
|---|
| | H-2AX |
|---|
| | |
|---|
| Organism | Rattus norvegicus |
|---|
| | Mus musculus |
|---|
| | Human |
|---|
| | |
|---|
| Group | nucleic acid binding |
|---|
|
|
 |
|
|
