Return to our Home Page


Technical Resources
Technical Information
Calbiochem Information
Inhibitor Resource
New Inhibitors
Apoptosis
Cell Division, Cell Cycle, and Cell Adhesion
Immobilized Inhibitors
Inhibitor Cocktails
InSolution Inhibitors
Inhibitor Libraries
InhibitorSelect Panels
Inhibitor Sets
Lipid Signaling
Neurobiology
Nitric Oxide
Phosphorylation Dephosphorylation
Protease
Other Inhibitors
Technical Tips

For decades, Calbiochem® has manufactured high quality inhibitors, biochemicals, antibodies, proteins, and kits that have been cited in thousands of peer-reviewed publications. To continue with our endeavor to offer products that fast track your research, we have recently introduced the InhibitorSelect™ Libraries and Signaling Pathway Panels that contain a collection of carefully selected, structurally diverse, and potent inhibitors in convenient and cost effective formats. InhibitorSelect™ products are suitable for a wide variety of applications and are provided with comprehensive documentation.

Product Overview


InhibitorSelect™ Libraries are well-characterized, pharmacologically active, and structurally diverse InSolution™ inhibitors in 96- or 384-well format and offer:

Rich and valuable data - Our unique and expert selection of structurally diverse, well-characterized, cell-permeable, and potent inhibitors helps you get the most out of your investment

Results the first time, every time - Stringent stability and HPLC purity testing on every batch of plates ensures reliable results in every experiment

Experience you can count on - Comprehensive documentation about each inhibitor, such as molecular structure, IC50 values, literature citations, and CAS number (where available), is provided at your fingertips

InhibitorSelect™ Signaling Pathway Panels are 12-16 carefully hand-picked inhibitors in one convenient package to help you elucidate specific steps in a signaling cascade and offer:

Cost savings - Each panel provides a number of pathway specific inhibitors at a fraction of what it would cost to purchase each inhibitor individually

Hassle-free results - Our best selection of inhibitors, a negative control (where applicable), DMSO, and a data sheet are provided in one convenient kit


Sample ApplicationsBack to top

The Right Tools for Many Applications – Keep Your Research on the Fast Track

Effective Screening of Inhibitors for Influence on Proliferation and Survival of Mouse Neural Stem Cells



Click table to view larger version.




Click table to view larger version.

Rapid Screening of Receptor Tyrosine Kinase (RTK) Inhibition Using InhibitorSelect™ Inhibitor Library I and WideScreen™ RTK pTyr and Total 7-plex Assay Kits on a Luminex® xMAP®Platform



Click table to view larger version.




Click table to view larger version.


Validation & Quality ControlBack to top

Maximize Your Results and Minimize Your Screening Cost - With Expertly Selected Inhibitors

Inhibitors in each InhibitorSelect™ Library have been expertly selected to ensure structural diversity, cell permeability, reversibility, and potency so that you get the most out of your investment. In addition, the purity of inhibitors provided in each batch of plates is confirmed by HPLC to ensure that you get results the first time and every time. Characteristics of three Akt inhibitors included in InhibitorSelect™ Libraries are shown to demonstrate the diversity and quality of inhibitors provided.
Akt Inhibitor V, Triciribine (Cat. No. 124012)


Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 (Cat. No. 124018)


Akt Inhibitor X (Cat. No. 124020)


Ordering Information & Documentation


InhibitorSelect™ Libraries

To download the SD files and list of individual inhibitors provided in each library please click the appropriate links below. 

Inhibitor Library I 96-Well plate
Inhibitor Library I-96.sdf
(223 KB) (Structure Data Format file, requires special program to open)
Inhibitor Library I-96 List (734 KB)
Inhibitor Library II 96-Well plate
Inhibitor Library II-96.sdf (217 KB) (Structure Data Format file, requires special program to open)
Inhibitor Library II-96 List
(717 KB)

Inhibitor Library I 384-Well plate
Inhibitor Library I-384.sdf (428 KB) (Structure Data Format file, requires special program to open)
Inhibitor Library I 384-well plate List (1.42 MB)

Description
96-well
Library I
96-well
Library II
96-well
Library III
384-well
Library I
Contains 80 inhibitors against mainly tyrosine, AGC, and atypical families of kinasesContains 80 inhibitors against mainly CMGC and CaMK families of kinasesContains 84 inhibitors against mainly Ser/Thr kinases and is complementary to 96-well Library ICombines inhibitors from 96-well Library I and II, for a total of 160 inhibitors in one 384-well plate
Size/Format
96-well
96-well
96-well
384-well
Cat. No.
Coming Soon!
ADK
x
x
Akt
x
x
x
AMPK
x
x
ATM
x
x
ATR
x
x
Aurora
x
x
x
x
Bcr-Abl
x
x
CaMK
x
x
x
Cdks
x
x
x
cFMS
x
x
Chk1,2
x
x
x
CK1,2
x
x
x
c-Met
x
x
DAG
x
x
DNA-PK
x
x
x
eEF2
x
x
EGFR
x
x
ERK
x
x
x
FLT3
x
x
GSK-3
x
x
x
IGFR
x
x
IKK
x
x
x
IP3K
x
x
IRAK
x
x
JAK
x
x
JNK
x
x
Lck
x
x
MAPK
x
x
x
MEK
x
x
x
MLCK
x
x
MNK1
x
x
p70 S6
x
x
P90 S6
x
x
PAK
x
x
PDGFR
x
x
PDK1
x
x
PI 3-K
x
x
x
PIKfyve
x
x
x
PIM
x
x
PKA
x
x
PKC
x
x
x
PKG
x
x
PKR
x
x
PLK
x
x
Rho
x
x
x
RIP
x
x
SK
x
x
Src
x
x
x
Syk
x
x
TGF-βR
x
x
Tp12
x
x
VEGFR
x
x
Wee1
x
x

InhibitorSelect™ Signaling Pathway PanelsBack to top

InhibitorSelect™ Pathway Panels contain 12-16 hand-picked inhibitors to help you elucidate specific steps in a signaling cascade. Best of all you’ll save money, since our focused selection of inhibitors is provided to you in one convenient kit at a fraction of what it would cost to purchase each inhibitor individually.
Signaling Pathway Panel

PI 3-K/Akt/mTOR

Cat. No.: 124031

ComponentsCat. No.
Akt Inhibitor IV124011
Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2124018
LY 294002440202
LY 303511440203
PDK1/Akt/Flt Dual Pathway Inhibitor521275
PI-103528100
PI 3-Kγ Inhibitor528106
PI 3-Kγ Inhibitor II528108
PI 3-Kα Inhibitor IV528111
PI 3-Kα Inhibitor VIII528116
Rapamycin553210
Ro-31-8220557520
Wortmannin681675
DMSOKP31817

Signaling Pathway Panel

EGFR

Cat. No.: 324839

ComponentsCat. No.
Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2124018
PD 153035234490
EGFR Inhibitor324674
Et-18-OCH3341207
JNK Inhibitor II420119
LY 294002440202
PD 98059513000
PD 168393513033
PP2529573
Rapamycin553210
SB 203580559389
AG 490658401
ZM 336372692000
DMSOKP31817

Signaling Pathway Panel

MAP Kinase

Cat. No.: 444189

ComponentsCat. No.
ERK Inhibitor II, FR180204328007
JNK Inhibitor II420119
JNK Inhibitor IX420136
MEK1/2 Inhibitor444939
MNK1 Inhibitor454861
MK2a Inhibitor475863
p38 MAP Kinase Inhibitor V506156
PD 98059513000
Raf Kinase Inhibitor IV553014
SB 203580559389
Tpl2 Kinase Inhibitor616373
ZM 336372692000
DMSOKP31817

Signaling Pathway Panel

NF-κB

Cat. No.: 481487

ComponentsCat. No.
BAY 11-7082196870
IKK Inhibitor VII401486
IRAK 1/4 Inhibitor407601
Histone Acetyltransferase Inhibitor II382110
Trichostatin A, Streptomyces sp.647925
MG-132474790
NEMO Binding Domain Peptide,
Cell-Permeable
480025
NF-κB SN50481480
PD 98059513000
PDK1/Akt-Flt Dual Pathway Inhibitor521275
TIRAP Inhibitor Peptide613570
Tpl2 Kinase Inhibitor616373
(5Z)-7-Oxozeaenol, Curvularia sp.499610
JNK Inhibitor II420119
DMSOKP31817

Signaling Pathway Panel

JAK/STAT

Cat. No.: 420138

ComponentsCat. No.
PD 153035234490
Indirubin Derivative E804402081
JAK Inhibitor I420099
JAK2 Inhibitor II420132
LY 294002440202
PP2529573
SHP1/2 PTPase Inhibitor, NSC-87877565851
STAT3 Inhibitor Peptide, Cell Permeable573096
STAT3 Inhibitor III, WP1066573097
STAT3 Inhibitor V, Stattic573099
STAT5 Inhibitor573108
AG 490658401
U0126662005
DMSOKP31817

Back to top