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For decades, Calbiochem® has manufactured high quality inhibitors, biochemicals, antibodies, proteins, and kits that have been cited in thousands of peer-reviewed publications. To continue with our endeavor to offer products that fast track your research, we have recently introduced the InhibitorSelect™ Libraries and Signaling Pathway Panels that contain a collection of carefully selected, structurally diverse, and potent inhibitors in convenient and cost effective formats. InhibitorSelect™ products are suitable for a wide variety of applications and are provided with comprehensive documentation. Product Overview
InhibitorSelect™ Libraries are well-characterized, pharmacologically active, and structurally diverse InSolution™ inhibitors in 96- or 384-well format and offer:
Rich and valuable data - Our unique and expert selection of structurally diverse, well-characterized, cell-permeable, and potent inhibitors helps you get the most out of your investment
Results the first time, every time - Stringent stability and HPLC purity testing on every batch of plates ensures reliable results in every experiment
Experience you can count on - Comprehensive documentation about each inhibitor, such as molecular structure, IC50 values, literature citations, and CAS number (where available), is provided at your fingertips
InhibitorSelect™ Signaling Pathway Panels are 12-16 carefully hand-picked inhibitors in one convenient package to help you elucidate specific steps in a signaling cascade and offer:
Cost savings - Each panel provides a number of pathway specific inhibitors at a fraction of what it would cost to purchase each inhibitor individually
Hassle-free results - Our best selection of inhibitors, a negative control (where applicable), DMSO, and a data sheet are provided in one convenient kit
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The Right Tools for Many Applications – Keep Your Research on the Fast Track
Effective Screening of Inhibitors for Influence on Proliferation and Survival of Mouse Neural Stem Cells
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Rapid Screening of Receptor Tyrosine Kinase (RTK) Inhibition Using InhibitorSelect™ Inhibitor Library I and WideScreen™ RTK pTyr and Total 7-plex Assay Kits on a Luminex® xMAP®Platform
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 Click table to view larger version.
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Maximize Your Results and Minimize Your Screening Cost - With Expertly Selected Inhibitors
Inhibitors in each InhibitorSelect™ Library have been expertly selected to ensure structural diversity, cell permeability, reversibility, and potency so that you get the most out of your investment. In addition, the purity of inhibitors provided in each batch of plates is confirmed by HPLC to ensure that you get results the first time and every time. Characteristics of three Akt inhibitors included in InhibitorSelect™ Libraries are shown to demonstrate the diversity and quality of inhibitors provided.
| Akt Inhibitor V, Triciribine (Cat. No. 124012) | |
| Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 (Cat. No. 124018) | |
| Akt Inhibitor X (Cat. No. 124020) | |
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Ordering Information & Documentation | |
InhibitorSelect™ Libraries
To download the SD files and list of individual inhibitors provided in each library please click the appropriate links below.
Inhibitor Library I 96-Well plate Inhibitor Library I-96.sdf (223 KB) (Structure Data Format file, requires special program to open) Inhibitor Library I-96 List (734 KB) Inhibitor Library II 96-Well plate Inhibitor Library II-96.sdf (217 KB) (Structure Data Format file, requires special program to open) Inhibitor Library II-96 List (717 KB)
Inhibitor Library I 384-Well plate Inhibitor Library I-384.sdf (428 KB) (Structure Data Format file, requires special program to open) Inhibitor Library I 384-well plate List (1.42 MB)
| Description | 96-well Library I | 96-well Library II | 96-well Library III | 384-well Library I | | Contains 80 inhibitors against mainly tyrosine, AGC, and atypical families of kinases | Contains 80 inhibitors against mainly CMGC and CaMK families of kinases | Contains 84 inhibitors against mainly Ser/Thr kinases and is complementary to 96-well Library I | Combines inhibitors from 96-well Library I and II, for a total of 160 inhibitors in one 384-well plate | | Size/Format | 96-well | 96-well | 96-well | 384-well | Cat. No. | | | Coming Soon! | | ADK | x | | x | | Akt | x | | x | x | AMPK | | x | | x | ATM | | x | | x | ATR | | x | | x | Aurora | x | x | x | x | Bcr-Abl | x | | | x | CaMK | | x | x | x | Cdks | | x | x | x | cFMS | x | | | x | Chk1,2 | | x | x | x | CK1,2 | | x | x | x | c-Met | x | | | x | DAG | x | | | x | DNA-PK | x | | x | x | eEF2 | x | | x | | EGFR | x | | | x | ERK | | x | x | x | FLT3 | x | | | x | GSK-3 | | x | x | x | IGFR | x | | | x | IKK | | x | x | x | IP3K | x | | x | | IRAK | x | | | x | JAK | x | | | x | JNK | | x | | x | Lck | x | | | x | MAPK | | x | x | x | MEK | | x | x | x | MLCK | | x | x | | MNK1 | | x | | x | p70 S6 | x | | | x | P90 S6 | x | | x | | PAK | x | | x | | PDGFR | x | | | x | PDK1 | x | | | x | PI 3-K | x | | x | x | PIKfyve | x | | x | x | PIM | x | | x | | PKA | x | | x | | PKC | x | | x | x | PKG | x | | x | | PKR | x | | | x | PLK | x | | x | | Rho | x | | x | x | RIP | | x | x | | SK | | x | | x | Src | x | x | | x | Syk | x | | | x | TGF-βR | x | | | x | Tp12 | x | | x | | VEGFR | x | | | x | Wee1 | x | | x | |
InhibitorSelect™ Pathway Panels contain 12-16 hand-picked inhibitors to help you elucidate specific steps in a signaling cascade. Best of all you’ll save money, since our focused selection of inhibitors is provided to you in one convenient kit at a fraction of what it would cost to purchase each inhibitor individually.
Signaling Pathway Panel
NF-κB
Cat. No.: 481487 | Components | Cat. No. | | BAY 11-7082 | 196870 | | IKK Inhibitor VII | 401486 | | IRAK 1/4 Inhibitor | 407601 | | Histone Acetyltransferase Inhibitor II | 382110 | | Trichostatin A, Streptomyces sp. | 647925 | | MG-132 | 474790 | NEMO Binding Domain Peptide, Cell-Permeable | 480025 | | NF-κB SN50 | 481480 | | PD 98059 | 513000 | | PDK1/Akt-Flt Dual Pathway Inhibitor | 521275 | | TIRAP Inhibitor Peptide | 613570 | | Tpl2 Kinase Inhibitor | 616373 | | (5Z)-7-Oxozeaenol, Curvularia sp. | 499610 | | JNK Inhibitor II | 420119 | | DMSO | KP31817 |
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