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Technical Resources
Resources for Peptide Synthesis
A guide to the selection of resins for solid phase peptide synthesis
Wall poster
>>
Amino acids
Allyl-protected amino-acid derivatives for Fmoc SPPS
New!
Updated!
A guide to the selection of building blocks for peptide synthesis
Fmoc-protected unusual amino acids
A summary of the Novabiochem collection of unusual amino acids
Optimized coupling procedures for unusual amino acids
Detailed methods for coupling hindered amino acids
Innovations 2/07: Synthesis of peptides containing methylated lysine residues
Detailed method for the synthesis of peptides containing methylated lysine residues
>>
Loading and cleavage protocols
Updated!
Boc-peptide resin cleavage protocols
Updated!
Fmoc-peptide resin cleavage protocols
Peptide resin loading protocols
Strategies for the synthesis of peptide aldehydes
Sulfonamide based safety-catch resins
>>
Coupling protocols
Epimerization-free fragment condensation with
pseudoproline (oxazolidine) dipeptides
Optimized protocols for the use of Fmoc-Dpr(ivDde)-OH
Optimized coupling procedures for unusual amino acids
Detailed methods for coupling hindered amino acids
The role of HOBt in coupling reactions
Synthesis of peptides containing methylated arginine residues
>>
Phosphopeptide synthesis
Phosphopeptide synthesis
Optimized protocols for the addition of Fmoc-Aaa(PO(OBzl)OH)-OH
Phosphopeptide synthesis using Fmoc-Tyr(PO(NMe<sub>2</sub>)<sub>2</sub>)-OH
>>
Synthesis of long or difficult peptides
Synthesis of β-amyloid using an isoacyl dipeptide
New!
Derivatives for enhancing peptide synthesis
Synthesis of the transmembrane region of bradykinin receptor b2
Synthesis of wild-type and phosphorylated phospholamban
The synergy of ChemMatrix resin® and pseudoproline building blocks renders Rantes, a complex aggregated chemokine
Smart peptide synthesis: Synthesis of the Rantes
Synthesis of neurotoxic prion peptide (106 - 126)
Synthesis of thymosin-α
1
using pseudoproline dipeptides.
Smart peptide synthesis: Synthesis of PADRE-Muc chimeric peptide
Synthesis of highly amyloidogenic human IAPP using pseudoproline dipeptides
Expediting convergent synthesis with pseudoproline dipeptides
Derivatives for the synthesis of difficult peptides
Synthesis of long peptides using pseudoproline dipeptides
Stepwise solid phase synthesis of a 120 residue peptide related to FAS death domain
Expediting the Fmoc solid phase synthesis of long peptides through the application of dimethyloxazolidine dipeptides
Guidelines for the use of pseudoproline dipeptides
Synthesis design using pseudoproline dipeptides
Exploring strategies for peptide synthesis
>>
Overcoming side-reactions
New derivatives for overcoming aspartimide formation
Overcoming aspartimide in Fmoc SPPS
New!
>>
Orthogonally protected amino acids
Orthogonally protected diamino acid derivatives
Protocols for selective removal of the ivDde protecting group
>>
Peptide ligation and labeling
A novel solid-phase linker strategy for the side-chain anchoring of arginine: an expeditious route to arginine 7-amido-4-methylcoumarins
New!
Solid phase synthesis of AMC-based enzyme substrates
New tools for SPPS of labeled peptides.
SPPS of biotinylated peptides
New tools for SPPS of FRET peptides
Selenocysteine in native ligations and as a dehydroalanine precursor
Synthesis of peptide thioesters for chemoselective ligation
Protocols for the use of sulfamyl resins to prepare peptide thioesters
Reagents for peptide ligation and labeling
Summary of Novabiochem's reagents for labeling and ligation
Introduction of PEG units to improve solubility of biotinylated model peptides
A versatile linker strategy to C-terminally labeled peptides
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©2008
Calbiochem
,
Novabiochem
, &
Novagen
are brands of EMD Chemicals Inc., an Affiliate of
Merck KGaA
, Darmstadt, Germany.