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Ubiquitin-Proteasome Interactive Pathway: Ubiquitin
 | | |  Ubiquitin Antibodies
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| Anti-Ubc9 Rabbit pAb |
IB, NOT FS, NOT PS |
human, mouse |
PC131 |
| Anti-Ubiquitin (Ab-1) Mouse mAb (6C1) |
IB |
bovine, human |
CC37 |
| Anti-Ubiquitin Rabbit pAb |
IB, IH, IP |
bovine, canine, chicken, Drosophila, E. coli, frog, guinea pig, hamster, human, monkey, mouse, rabbit, rat, sheep, yeast |
662099 |
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| | | Ubiquitin Assay Kits
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| Ubiquitin Protein Conjugation Kit |
662096 |
| Ubiquitinated Protein Enrichment Kit |
662200 |
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| | | Ubiquitin Enzymes
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| Fraction II, Rabbit Reticulocytes |
344260 |
| Isopeptidase T, Rabbit |
419700 |
| Ubiquitin C-Terminal Hydrolase, Rabbit |
662090 |
| Ubiquitin K48R, His•Tag®, Human, Recombinant, E.coli |
662064 |
| Ubiquitin, GST-Fusion, Recombinant, E. coli |
662057 |
| Ubiquitin, His•Tag®, Recombinant, E. coli |
662060 |
| Ubiquitin-Activating Enzyme E1, Rabbit |
662070 |
| Ubiquitin-Agarose |
662080 |
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| | | Ubiquitin Substrates
| | | | Additional Information | | | | | | | | |
| Protein : Ub
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| Connectivity | 1 |
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| Notes | This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. |
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| Hugo ID | 12463 |
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| Name | Ub |
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| Description | ubiquitin B |
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| URN | urn:agi-llid:7314 |
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| GO Cellular Component | nucleus |
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| Cell Localization | Cytoplasm |
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| | Nucleus |
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| GO Biological Process | protein modification |
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| Alias | Loc192255 |
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| | polyubiquitin |
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| | Ubb |
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| | Ubb2 |
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| | TI-225 |
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| | Ubc |
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| | ubiquitin B |
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| | MGC8385 |
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| | UBIQ |
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| | Ub |
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| | polyubiquitin B |
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| | ubiquitin B precursor |
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| | UBIQ_HUMAN |
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| | Ubiquitin |
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| | similar to polyubiquitin 10 |
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| | similar to polyubiquitin 10 - rat |
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| Organism | Rattus norvegicus |
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| | Mus musculus |
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| | Human |
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| Pathway | NFkB |
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| | GSK3 |
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| | Ubiquitin |
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