		Technical Resources

		Technical Information

		Calbiochem Information

		Interactive Pathways

		Protein Tyrosine Kinase

		VEGF

VEGF Interactive Pathway: Ras

�

Ras Antibodies

Product

Application

Species Reactivity

Cat. No.

Anti-Ras (31-43) Rabbit pAb ELISA, IB, IH, IP human 553571

Anti-c-H-Ras (Ab-1) Mouse mAb (F235-1.7.1) FS, IB, IF, IP, PS human, mouse, rat OP23

Anti-c-H-Ras (Ab-1) Mouse mAb (F235-1.7.1) FS, IB, IF, IP, PS human, mouse, rat OP23T

Anti-c-K-Ras (Ab-1) Mouse mAb (234-4.2) FS, IB, IP, PS human, mouse, rat OP24

Anti-c-K-Ras (Ab-1) Mouse mAb (234-4.2) FS, IB, IP, PS human, mouse, rat OP24T

Anti-c-N-ras (Ab-1) Mouse mAb (F155-227) FS, IB, IP, PS human, mouse, rat OP25

Anti-v-H-Ras (Ab-1) Rat mAb (Y13-259) FS, IB, IF, IP, NT, PS human, mouse, rat OP01

Anti-v-H-Ras (Ab-1) Rat mAb (Y13-259) FS, IB, IF, IP, NT, PS human, mouse, rat OP01L

Anti-v-H-Ras (Ab-1) Rat mAb (Y13-259) Agarose Conjugate IP human, mouse, rat OP01A

Anti-v-H-Ras (Ab-2) Rat mAb (Y13-238) IF, IP, NOT IB, NOT NS human, mouse, rat OP04

Anti-Pan-Ras (Ab-1) Mouse mAb (F132-62) FS, IF, IP, NOT IB, PS human, mouse, rat OP21

Anti-Pan-Ras (Ab-2) Mouse mAb (F111-85) IB, IP human, mouse, rat OP22

Anti-Pan-Ras (Ab-3) Mouse mAb (RAS 10) FC, FS, IB, IF, IP, PS human, mouse, rat OP40

Anti-Pan-Ras (Ab-4) Mouse mAb (RAS 11) IB, IP human, mouse, rat OP41

Anti-Pan-Ras Asp¹² (Ab-1) Rabbit pAb IB human, mouse, rat PC10L

Anti-Pan-Ras Val¹² (Ab-1) Mouse mAb (DWP) ELISA, IB, IP human, mouse, rat OP38

�

Ras Proteins/Peptides

Product

Cat. No.

c-H-Ras, GST-Fusion, Human, Recombinant, E. coli 553329

p21 H-Ras (Gly¹²) Western Blot Standard WA01

K-ras Val¹² Western Blot Standard WA04

Ras, Human, Recombinant, CVLL Type, E. coli 553322

Ras, Human, Recombinant, Wild-Type, E. coli 553325

�

Additional Information

�

Protein : HRAS


Name	HRAS
Description	v-Ha-ras Harvey rat sarcoma viral oncogene homolog
Owner	Public
URN	urn:agi-llid:3265
Connectivity	141
Notes	Harvey ras; binds GTP and transmits signals from growth factor receptors
Hugo ID	5173


Microarray ID	1424132_at
	101005_at
	1422407_s_at
	160536_at
	z50013_s_at
	A_51_P357664
	V00574
	212983_at
	35701_at
	1590_s_at
	V00574_s_at
	A_23_P98183
	M837
	CA514
	OH2092
	Msa.2210.0_at
	A_65_P03001
	H3091H05-3
	NM_008284
	RC_AA443316_s_at
	J00277_at
	A_32_P864748
	I_3249153
	A_32_P322504
	I_3249044
	I_929316


GenBank ID	47117696
	34222246
	51468897
	14210277
	14210278
	AAB50559
	AAD56718
	AAF74295
	AAH11083
	AAH50837
	AAH61885
	AAP21090
	AAQ81319
	AAT72335
	AB072334
	AF081118
	AF268311
	AJ437023
	AK183914
	AK218213
	AY373386
	AY490389
	BAB88314
	BAB88315
	BAB88316
	BC011083
	BC050837
	BC061885
	CAA90306
	CAD24593
	NC_000073
	NM_008284
	NP_032310
	NT_039436
	Q61411
	S74119
	U89950
	Z50013
	AAA35685
	AAA35687
	AAA36148
	AAA36555
	AAA52693
	AAB02605
	AAB29639
	AAD13953
	AAH06499
	AAH95471
	AAK56963
	AAM12630
	AAV38228
	AF375987
	AF493916
	AJ437024
	BC006499
	BC095471
	BM801632
	BT019421
	CAA25624
	CAA29078
	CAA34461
	CAA37384
	CAD24594
	CAG38816
	CAG47067
	CR536579
	CR542271
	J00277
	K00654
	M17087
	M17232
	M19990
	M26261
	NC_000011
	NM_005343
	NM_176795
	NP_005334
	NP_789765
	NT_035113
	NT_086778
	P01112
	S64261
	S68580
	X01227
	X05564
	X16438
	X53291
	190890
	190891
	553637
	131869
	68929
	5031597
	11386203
	NT_081122
	CAA23837
	UNC: Harvey ras; binds GTP and transmits signals from growth factor receptors
	NW_043401
	XM_215123
	XP_215123
	M61016
	206568
	51762690
	6680270
	6680271
	707062
	30102398
	895862
	895863
	34732778
	34732779
	15029733
	15029734
	2500063
	180537
	463093
	180531
	180533
	184387
	465130
	186761
	553519
	402830
	4261653
	544856
	544857
	35890
	35891
	29944
	29945
	35098
	825697
	20147724
	20147725
	28551960
	28551961
	33873529
	13676334
	19118455
	54695711
	54695712
	49168641
	49168642
	49457535
	49457536
	190919
	V00574
	51493057
	47117697
	4885425


Chromosome position	11p15.5
	7 72.2 cM


GO ID	0005524
	GO:0003930
	GO:0003925
	GO:0003924
	GO:0005525
	GO:0005524
	GO:0007264
	GO:0008151
	GO:0007265
	GO:0000074
	GO:0006935
	GO:0007397
	GO:0007166
	GO:0007148
	GO:0006928
	GO:0007165
	GO:0000157
	GO:0005737
	GO:0005886
	0006897
	0007265
	0007569
	0050875
	0000074
	0000166
	0003924
	0005515
	0005525
	0005737
	0005886
	0006928
	0006935
	0007166
	0007264
	0009887
	0015031


Alias	ras
	Hras-1
	RASH
	p21
	transforming protein p21 (H-ras-1)
	similar to transforming protein H-Ras - mouse
	similar to transforming protein H-Ras
	similar to transforming H-Ras - mouse
	H-RAS
	C-H-RAS
	HA-RAS
	Harvey rat sarcoma virus oncogene 1
	Harvey-ras
	HRAS1
	H-RasIDX
	RASH1
	Transforming protein P21/H-RAS-1
	v-Ha-ras Harvey rat sarcoma viral oncogene homolog
	RASH_HUMAN
	Harvey rat sarcoma virus oncogene I
	Harvey rat sarcoma viral (v-Ha-ras) oncogene homolog
	RASH I
	Transforming protein P21/H-RAS I
	p21 RAS
	H-Ras4A
	1BKD_R
	1HE8_B
	1K8R_A
	1LFD_D
	1NVU_Q
	1NVU_R
	1NVV_Q
	1NVV_R
	1NVW_Q
	1NVW_R
	1NVX_Q
	1WQ1_R
	6Q21_A
	6Q21_B
	6Q21_C
	6Q21_D
	H-ras-GDP
	H-ras-GTP
	HRAS I
	1BKD_Rs
	1LFD_Ds
	1NVU_Qs
	1NVU_Rs
	1NVV_Qs
	1NVV_Rs
	1NVW_Qs
	1NVW_Rs
	1NVX_Qs
	C-H-RASs
	c-bas/has
	c-h-ras-1 protein n-terminal fragment
	n-ras oncogene (aa 1-37)
	n-ras oncogene
	c-has/bas p21 protein
	c-ras-ki-2 protein
	c-h-ras-1 protein n-terminal fragment (37 aa)
	g1iii6 n-ras
	H(RAS)
	HRAS
	H RAS


Organism	Rattus norvegicus
	Mus musculus
	Homo sapiens
	Human


MedLine Reference	10869344
	10871846
	12446704
	12878730
	10842192
	10848592
	11022048
	8607982
	9020890
	9880516


LocusLink ID	15461
	3265
	293621
	24466


FunctionalClass	GTP binding
	GTPase
	nucleotide binding
	protein binding


RGD ID	2827


Hugo Symbol	HRAS


Unigene ID	Mm.334313
	Hs.505033
	Hs.37003
	Mm.6793


Keyword	desmoplakin
	oncogene
	RAS small monomeric GTPase
	GEF
	gtpase
	integrin
	small monomeric GTPase
	plasma membrane
	map kinase
	activated blood coagulation factor XIV
	desmoplakins


GO Cellular Component	cytoplasm
	plasma membrane
	peripheral plasma membrane protein


GO Molecular Function	RAS small monomeric GTPase activity
	small monomeric GTPase activity
	GTPase activity
	GTP binding
	ATP binding
	GTP binding activity
	ATP binding activity


Cell Localization	Cytoplasm
	Plasma membrane


Pathway	p40 MAPK
	CREB signaling
	Antiapoptotic Pathways From IGF-1R
	Integrin Signaling
	NGF signaling
	Vasopressin
	Substance P
	opioids OPRM1
	opioids OPRK1
	opioids OPRD1
	Nociceptin
	Neurotensin
	HGF
	Endothelin
	Bombesin
	ACVR1B -> JUNB signalling pathway
	ACVRL1 -> STAT1 signalling pathway
	ACVRL1 -> MADH1 signalling pathway
	ACVRL1 -> MADH2 signalling pathway
	TNFRSF10B -> REL signalling pathway
	NTRK1 -> MADH3 signalling pathway
	OPRM1 -> JUNB signalling pathway
	TNFRSF1A -> FOS signalling pathway
	TNFRSF1A -> CREB1 signalling pathway
	TNFRSF1B -> STAT1 signalling pathway
	TNFRSF1B -> CREB1 signalling pathway
	ADRB2 -> CREB1 signalling pathway
	AGTR2 -> MYC signalling pathway
	IL2RB -> FOS signalling pathway
	IL4R -> MYC signalling pathway
	ITGAM -> JUN signalling pathway
	ITGAM -> SPI1 signalling pathway
	ITGAM -> CEBPB signalling pathway
	ITGAM -> RELA signalling pathway
	KDR -> HIF1A signalling pathway
	KDR -> HSPCA signalling pathway
	KDR -> ATF1 signalling pathway
	KDR -> ETS1 signalling pathway
	KDR -> EGR3 signalling pathway
	KIT -> MITF signalling pathway
	SEMA6B -> FOS signalling pathway
	LDLR -> SREBF1 signalling pathway
	CD4 -> STAT6 signalling pathway
	CD28 -> BCL6 signalling pathway
	CD28 -> FOS signalling pathway
	CD28 -> TCF3 signalling pathway
	CD28 -> CREBBP signalling pathway
	CD28 -> RELA signalling pathway
	CD28 -> EGR2 signalling pathway
	TNFRSF5 -> CEBPA signalling pathway
	EPHA1 -> JUN signalling pathway
	EPHB3 -> MLLT4 signalling pathway
	EPOR -> MYC signalling pathway
	EPOR -> SPI1 signalling pathway
	EDAR -> EGR1 signalling pathway
	FCGR2B -> GATA4 signalling pathway
	FLT3 -> HSPCA signalling pathway
	GRIN1 -> FOS signalling pathway
	GRIN1 -> CREB1 signalling pathway
	GRM2 -> FOS signalling pathway
	GRM5 -> FOS signalling pathway
	GRM5 -> CREB1 signalling pathway
	GRM5 -> EGR1 signalling pathway
	PECAM1 -> SP1 signalling pathway
	PECAM1 -> RBL2 signalling pathway
	PTPRA -> TEAD1 signalling pathway
	PTPRC -> NFATC2 signalling pathway
	PTPRE -> EGR1 signalling pathway
	DRD2 -> CREB1 signalling pathway
	RET -> HSF1 signalling pathway
	RET -> CREB1 signalling pathway
	MET -> MAX signalling pathway
	AGT-LRP2
	BDNF-NCAM1
	BDNF-NGFR
	BDNF-NTRK1
	BDNF-NTRK2
	BDNF-NTRK3
	CSF1-CSF1R
	CSF1-IL6R
	CSF1-TNFRSF5
	CSF2-CSF2RA
	CSF3-IL6R
	EGF-ERBB2
	EGF-ERBB3
	EGF-ERBB4
	EGF-LRP8
	EGF-NGFR
	EPO-EPOR
	F2-ITGAV
	F2-LRP1
	F2-LRP2
	F2-THBD
	FGF2-CD44
	FGF2-FGFR1
	FGF2-FGFR2
	FGF2-FGFR3
	FGF2-GPC1
	FGF2-TGFBR3
	IFNB1-IFNAR1
	IFNB1-IFNAR2
	IGF1-BST1
	IGF1-IGF2R
	IGF1-LRP5
	IL1A-IL1RAP
	IL1B-HLA-DRB1
	IL2-IL15RA
	IL2-IL2RA
	IL2-IL2RB
	IL2-IL4R
	IL3-CD8A
	IL3-CSF2RB2
	IL3-EPOR
	IL3-IL3RA
	IL4-FCER2
	IL5-IL5RA
	IL5-IL6ST
	IL6-IL6R
	IL6-IL6ST
	IL6-LIFR
	IL6-TNFRSF5
	INHBA-ACVR1B
	INHBA-ACVR2B
	INHBA-ACVRL1
	INS-EGFR
	INS-HLA-DRB1
	INS-TFRC
	NGFB-NGFR
	NGFB-NTRK1
	NGFB-NTRK2
	NGFB-NTRK3
	NTF3-CNTFR
	NTF3-NGFR
	NTF3-NTRK1
	NTF3-NTRK2
	NTF3-NTRK3
	TGFA-EGFR
	TGFB1-ACVR1
	TGFB1-ACVR1B
	TGFB1-ACVR2
	TGFB1-ACVR2B
	TGFB1-ACVRL1
	TGFB1-BMPR1B
	TGFB1-CD44
	TGFB1-IGF2R
	TGFB1-IL6R
	TGFB1-M6PR
	TGFB1-SELE
	TGFB1-SELL
	TGFB1-TGFBR1
	TGFB1-TGFBR2
	TGFB1-TGFBR3
	TNF-IL15RA
	TNF-NGFR
	TNF-TNFRSF1B
	VEGF-CD44
	VEGF-EGFR
	VEGF-FLT1
	VEGF-FLT4
	VEGF-GPC1
	VEGF-IL1R1
	VEGF-KDR
	CB0479 MAPK
	CB0480 Insulin


GO Biological Process	Ras protein signal transduction
	cell aging
	cellular physiological process
	endocytosis
	cell motility
	cell surface receptor linked signal transduction
	chemotaxis
	organogenesis
	protein transport
	regulation of progression through cell cycle
	small GTPase mediated signal transduction
	regulation of cell cycle
	cell growth and/or maintenance
	histogenesis and organogenesis
	cell shape and cell size control
	signal transduction


Group	Gtp binding proteins


State	isofrom 1
	isoform 2
	H-RasIDX
	Ras-GDP
	Ras-GTP


MGI ID	96224


Swiss-Prot Accession	P01112


OMIM ID	190020
	109800
	OMIM:190020
	OMIM:109800


Source	Curated
	ResNet
	BIND

�