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Insulin Pathway: 4EBP1
 | | |  4EBP1 Antibody
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| Anti-4EBP1/PHAS-I (101-118) Rabbit pAb |
GS, IB |
human, mouse, rat |
516676 |
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| | | 4EBP1 Peptide/Substrate
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| 4EBP1/PHAS-I, Rat, Recombinant |
516675 |
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| | | 4EBP1 Protein/Enzyme
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| 4EBP1, His•Tag®, Human, Recombinant, S. frugiperda |
516678 |
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| | | | Additional Information | | | | | | | | |
| Protein : 4EBP1 (EIF4EBP1)
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| Name | 4EBP1 (EIF4EBP1) |
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| Description | eukaryotic translation initiation factor 4E binding protein 1 |
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| Owner | Public |
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| URN | urn:agi-llid:1978 |
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| Connectivity | 63 |
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| Notes | SUMMARY: forms a complex with eukaryotic initiation factor-4E (eIF-4E) and is an intracellular target for insulin and growth factors [RGD] |
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| Hugo ID | 3288 |
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| Microarray ID | 1386888_at |
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| | u05014_at |
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| | u05014_g_at |
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| | A_43_P12961 |
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| | 100636_at |
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| | 1417562_at |
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| | 1434976_x_at |
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| | u28656_s_at |
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| | A_51_P330428 |
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| | A_52_P283674 |
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| | 31597_r_at |
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| | 221539_at |
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| | 54152_at |
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| | rc_aa290674_s_at |
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| | A_23_P22224 |
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| | A_14_P138830 |
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| | OR1519 |
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| | OH1167A |
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| | AH448 |
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| | RA0695 |
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| Chromosome position | 8 8.0 cM |
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| | 8p12 |
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| | 16q12.3 |
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| GO ID | 0008190 |
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| | 0005515 |
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| | 0030371 |
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| | 0008286 |
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| | 0017148 |
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| | 0045947 |
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| | 0006417 |
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| | 0006445 |
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| | 0006446 |
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| | 0008372 |
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| Alias | Eif4ebp1 |
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| | PIR:A55258 |
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| | 4EBP Is |
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| | 4E-BP I |
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| | Eif4ebp I |
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| | 4E-binding protein I |
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| | Eukaryotic translation initiation factor 4Ebinding protein I |
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| | eukaryotic translation initiation factor 4E binding protein I |
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| | eIF4E -binding protein I |
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| | 4EBP I |
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| | 4EBP1 |
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| | P/OKCL6 |
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| | Eukaryotic translation initiating factor 4Ebinding protein I |
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| | Eukaryotic translation initiating factor 4Ebinding protein 1 |
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| | eukaryotic translation initiating factor 4E binding protein I |
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| | eukaryotic translation initiating factor 4E binding protein 1 |
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| | 4E-binding protein 1 |
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| | 4E-BP1 |
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| | PHAS-I |
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| | Eukaryotic translation initiation factor 4Ebinding protein 1 |
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| | eukaryotic translation initiation factor 4E binding protein 1 |
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| | eIF4E -binding protein 1 |
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| | insulin-stimulated phosphoprotein PHAS-I |
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| Organism | Rattus norvegicus |
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| | Mus musculus |
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| | Homo sapiens |
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| | Human |
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| FunctionalClass | eukaryotic initiation factor 4E binding |
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| | protein binding |
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| | translation repressor |
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| GO Cellular Component | cellular component unknown |
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| Cell Localization | Cytoplasm |
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| | Nucleus |
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| Pathway | Insulin Receptor Signaling |
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| | AGT-LRP2 |
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| | BDNF-NCAM1 |
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| | BDNF-NTRK2 |
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| | BDNF-NTRK3 |
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| | CSF2-CSF2RA |
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| | EGF-ERBB2 |
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| | EGF-ERBB3 |
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| | EGF-ERBB4 |
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| | EGF-LRP8 |
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| | EGF-NGFR |
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| | HGF-CD44 |
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| | HGF-FGFR2 |
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| | HGF-IL6R |
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| | HGF-MET |
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| | IFNA1-CR2 |
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| | IFNA1-IFNAR1 |
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| | IFNA1-IFNAR2 |
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| | IGF1-BST1 |
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| | IGF1-IGF2R |
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| | IGF1-LRP5 |
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| | IGF2-IGF2R |
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| | IL6-IL6R |
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| | IL6-LIFR |
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| | INS-EGFR |
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| | INS-HLA-DRB1 |
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| | INS-TFRC |
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| | NGFB-NTRK2 |
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| | NGFB-NTRK3 |
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| | VEGF-CD44 |
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| | VEGF-EGFR |
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| | VEGF-FLT1 |
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| | VEGF-FLT4 |
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| | VEGF-GPC1 |
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| | VEGF-IL1R1 |
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| | CB0480 Insulin |
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| | mTOR |
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| | simple mTOR |
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| GO Biological Process | insulin receptor signaling pathway |
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| | negative regulation of protein biosynthesis |
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| | negative regulation of translational initiation |
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| | regulation of protein biosynthesis |
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| | regulation of translation |
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| | regulation of translational initiation |
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