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		Protein Tyrosine Kinase

		Insulin

Insulin Pathway: GLUT4

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Additional Information

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Protein : GLUT4 (SLC2A4)


Name	GLUT4 (SLC2A4)
Description	solute carrier family 2 (facilitated glucose transporter), member 4
Owner	Public
URN	urn:agi-llid:6517
Connectivity	102
Notes	SUMMARY: transports glucose; may play a role in insulin response [RGD]
Hugo ID	11009


Microarray ID	1367989_at
	1388958_a_at
	d28561_s_at
	A_42_P757990
	102314_at
	102511_f_at
	1415958_at
	1415959_at
	msa.728.0_at
	msa.728.0_g_at
	A_51_P217498
	M91463
	206603_at
	37076_at
	M91463_rna1_at
	m20747_s_at
	A_32_P458036
	A_23_P107350
	A_14_P132965
	OR3555
	H312
	OH2959
	MA584


GenBank ID	34872015
	AAA41451
	AAA41453
	AAA65751
	AAH85757
	BAA05911
	BC085757
	CAA32879
	D28561
	J04524
	L36125
	M25482
	NC_005109
	NM_012751
	NP_036883
	NW_047334
	P19357
	X14771
	AAA37753
	AAH14282
	AB008453
	AK137607
	AK138832
	AK160882
	AK164310
	AL596185
	BAB03251
	BAE23429
	BAE37730
	BC014282
	CAI35157
	M23383
	M29660
	NC_000077
	NM_009204
	NP_033230
	NT_096135
	AAA52569
	AAA59189
	AAH69615
	AAH69621
	BC069615
	BC069621
	CAA41399
	M20747
	M91463
	NC_000017
	NM_001042
	NP_001033
	NT_010718
	NT_086857
	P14672
	X58489
	P14142
	6980957
	6980958
	536863
	536864
	55250154
	55250155
	464195
	538355
	204979
	204980
	537942
	537943
	56501
	56502
	121763
	51828859
	6678014
	6678015
	193708
	9392289
	9392290
	15679950
	15679951
	193706
	309281
	17380401
	4507010
	4507011
	51474476
	183295
	183296
	402583
	402584
	46854876
	46854877
	46854754
	46854755
	186552
	307076
	121761
	51474229


Chromosome position	10q24
	17p13
	11 40.0 cM


GO ID	0005360
	0005768
	0005792
	0005886
	0006810
	0009897
	0012506
	0016021
	0030659
	0042593
	0048471
	0016020
	0005215
	0005351
	0005355
	0005624
	0005887
	0005975
	0008643
	0015758
	0000299


Alias	Glucose transporter 4 insuline-responsive
	solute carrier family 2 (facilitated glucose transporter) member 4
	Glut-4
	facilitated glucose transporter 4
	Glucose transporter 4, insuline-responsive
	GLUT4
	Slc2a4
	solute carrier family 2 (facilitated glucose transporter), member 4
	solute carrier family 2 , member 4
	facilitated glucose transporter IV
	solute carrier family 2 (facilitated glucose transporter), member IV
	solute carrier family 2 , member IV
	Glucose transporter type 4, insulin-responsive


Organism	Human
	Rattus norvegicus
	Homo sapiens
	Mus musculus


MedLine Reference	11500317
	12450403
	9059504
	2649253
	10444069
	12297296
	12466851
	12490950
	12832401
	14562105
	15247266
	7675081


LocusLink ID	25139
	20528
	6517


FunctionalClass	insulin-responsive hydrogen:glucose transporter
	glucose transporter
	sugar porter
	transporter


RGD ID	2711


Hugo Symbol	SLC2A4


Unigene ID	Rn.1314
	Hs.371905
	Mm.10661
	Hs.549064


GO Cellular Component	integral to plasma membrane
	membrane
	membrane fraction
	cytoplasmic vesicle membrane
	endosome
	external side of plasma membrane
	integral to membrane
	integral to membrane of membrane fraction
	microsome
	perinuclear region
	plasma membrane
	vesicle membrane


Cell Localization	Plasma membrane


Pathway	Insulin pathway
	Insulin Receptor Signaling
	EGF-ERBB2
	EGF-ERBB3
	EGF-ERBB4
	EGF-LRP8
	EGF-NGFR
	GH1-IGF1R
	IGF1-BST1
	IGF1-IGF2R
	IGF1-LRP5
	IGF2-IGF1R
	IGF2-IGF2R
	IL6-LIFR
	INS-EGFR
	INS-HLA-DRB1
	INS-TFRC
	NRG1-CD44
	TNF-IL15RA
	TNF-NGFR
	TNF-TNFRSF1B
	CB0480 Insulin


GO Biological Process	carbohydrate metabolism
	carbohydrate transport
	glucose transport
	glucose homeostasis
	transport


Group	Transporters


MGI ID	95758


Swiss-Prot Accession	P14672


OMIM ID	OMIM:138190
	138190


Source	Curated