Return to our Home Page

Technical Resources
Technical Information
Calbiochem Information
Interactive Pathways
Protein Tyrosine Kinase
Insulin
   
Quick Order Shopping Cart
Email a Link to this Page Help
Insulin Pathway: GSK3b
 
GSK-3b Antibodies
Sort by product
Reverse sort by product
 Product
Sort by Application
Reverse sort by Application
 Application
Sort by Species Reactivity
Reverse sort by Species Reactivity
 Species Reactivity
Sort by catalog number
Reverse sort by catalog number
 Cat. No.
Anti-GSK-3a/b Mouse mAb (1H8) ELISA, IB bovine, canine, hamster, human, mouse, ovine, porcine, rabbit, rat 368662
Anti-GSK-3b, C-Terminal (334-348) Rabbit pAb ELISA, IB, IP human, mouse, rat 361528
PhosphoDetect™ Anti-GSK-3a/b (pTyr279/216) Rabbit pAb DB, ELISA, IB, IC human, mouse, rat ST1013
PhosphoDetect™ Anti-GSK-3b (pSer9) (Ab-1) Rabbit pAb Rabbit pAb DB, ELISA, IB human, rat, Xenopus PC242
PhosphoDetect™ Anti-GSK-3b, (pSer9) Rabbit pAb IB human, rat PS1018
PhosphoDetect™ Anti-GSK3b (pSer9) Mouse mAb (2D3) ELISA, IB human, mouse 361527
 
GSK-3b Enzymes
Sort by product
Reverse sort by product
 Product
Sort by catalog number
Reverse sort by catalog number
 Cat. No.
GSK-3a, GST-Fusion, Human, Recombinant, S. frugiperda 361523
GSK-3b, His•Tag®, Human, Recombinant, E. coli 361524
GSK-3b, Rabbit Skeletal Muscle, Recombinant, E. coli 361526
 
GSK-3b Inhibitors
Sort by product
Reverse sort by product
 Product
Sort by catalog number
Reverse sort by catalog number
 Cat. No.
Aloisine A 128125
Aloisine, RP106 128135
Alsterpaullone 126870
Alsterpaullone, 2-Cyanoethyl 126871
1-Azakenpaullone 191500
Cdk1/2 Inhibitor III 217714
Cdk1/5 Inhibitor 217720
FRATtide 344265
GSK-3 Inhibitor XV 361558
GSK-3 Inhibitor IX 361550
InSolution™ GSK-3 Inhibitor IX 361552
GSK-3 Inhibitor IX, Control, MeBIO 361556
GSK-3 Inhibitor X 361551
GSK-3 Inhibitor XIII 361555
GSK-3b Inhibitor I 361540
GSK-3b Inhibitor II 361541
GSK-3b Inhibitor III 361542
GSK-3b Inhibitor VII 361548
GSK-3b Inhibitor VIII 361549
InSolution™ GSK-3b Inhibitor VIII 361557
GSK-3b Inhibitor XI 361553
GSK-3b Inhibitor XII, TWS119 361554
GSK-3b Peptide Inhibitor 361545
GSK-3b Peptide Inhibitor, Cell-permeable 361546
GSK-3b Inhibitor VI 361547
GSK-3 Inhibitor XVII  NEW! 361560
Indirubin-3′-monoxime 402085
Indirubin-3′-monoxime, 5-Iodo- 402086
Indirubin-3′-monoxime-5-sulphonic Acid 402088
Isogranulatimide 371957
Kenpaullone 422000
Ro-31-8220 557520
 
GSK-3b Kit
Sort by product
Reverse sort by product
 Product
Sort by Format
Reverse sort by Format
 Format
Sort by Form
Reverse sort by Form
 Form
Sort by Sensitivity
Reverse sort by Sensitivity
 Sensitivity
Sort by Assay Range
Reverse sort by Assay Range
 Assay Range
Sort by Assay Time
Reverse sort by Assay Time
 Assay Time
Sort by Sample Type
Reverse sort by Sample Type
 Sample Type
Sort by catalog number
Reverse sort by catalog number
 Cat. No.
GSK-3b ELISA Kit 96-well plate 96 Tests < 0.26 ng/ml 0.39-25 ng/ml 4 h CBA068
PhosphoDetect™ GSK-3b (pSer9) ELISA Kit 96-well plate 96 Tests < 0.4 U/ml 1.6-100 U/ml 4 h CBA069
 
GSK-3b Substrates
Sort by product
Reverse sort by product
 Product
Sort by catalog number
Reverse sort by catalog number
 Cat. No.
GSK-3b Substrate 361530
 
Additional Information
 
 
 
 

Protein : GSK3B

Name GSK3B
Description glycogen synthase kinase 3 beta
Owner Public
URN urn:agi-llid:2932
Connectivity 200
Notes Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms, alpha (GSK3A; MIM 606784) and beta, show a high degree of amino acid homology (Stambolic and Woodgett, 1994 [PubMed 7980435]). GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation (Plyte et al., 1992 [PubMed 1333807]).[supplied by OMIM]
Hugo ID 4617
Microarray ID 1370267_at
x53428cds_s_at
x73653_at
A_42_P620042
1451020_at
msa.26665.0_s_at
A_65_P08426
A_51_P514412
A_51_P288428
L33801
40645_at
209945_s_at
226183_at
226191_at
240562_at
242336_at
1253_at
L33801_at
A_23_P251342
A_14_P122983
A_14_P101281
A_14_P121901
A_14_P106664
A_32_P879593
CA116
OH1506
OR3115A
GenBank ID XM_489542
AAD39258
AAH06936
AAH60743
AB066114
AF156099
AK005170
AK020183
AK021230
AK078822
AK088784
AK148995
AK154293
AK164048
AK170965
AK171482
AK186943
AK190946
BAD86827
BAE32494
BAE42146
BAE42483
BC006936
BC032976
BC060743
NC_000082
NM_019827
NP_062801
NT_082362
NT_096987
Q9WV60
AAA66475
AAC69340
AAD48517
AAH00251
AAH12760
AF074333
AF098789
BC000251
BC012760
CAG38748
CR536510
L33801
NC_000003
NM_002093
NP_002084
NT_005612
NT_086640
P49841
CAA37519
CAA52020
NC_005110
NM_032080
NP_114469
NW_047356
P18266
X53428
X73653
XP_489542
38080799
51769477
51769478
51769687
58000432
9790077
57834171
57834172
7025914
7025915
12837503
12860689
12862052
26098123
26104937
13905273
13905274
22766803
38511427
38511428
11133187
34869631
14091769
14091770
56333
56334
402651
402652
125374
5730335
3800882
3800883
12652980
12652981
39644670
39644671
49168505
49168506
529236
529237
20455502
1082745
37550867
21361339
21361340
51464124
5870849
Chromosome position 3q13.3
11q21
16 B4
GO ID 0000320
0004672
0004674
0005515
0005634
0005829
0006611
0006916
0006950
0008013
0008283
0009887
0016301
0045444
0050321
0000166
0004696
0005524
0005977
0006468
0016055
0016740
0004682
0004691
0005737
0006917
0007163
0030010
0045892
Alias GSK-3 beta
8430431H08Rik
Glycogen synthase kinase-3 beta
Gsk3b
C86142
expressed sequence C86142
KG3B_HUMAN
GSK III
RIKEN cDNA 8430431H08 gene
7330414F15Rik
KG3B
GSK-3beta
protein kinase
GSK3beta
glycogen synthase kinase 3 beta
GSK3
GSK3-beta
GSK IIIs
C86142s
RIKEN cDNA 7330414F15 gene
GSK-3
Organism Homo sapiens
Mus musculus
Rattus norvegicus
Human
MedLine Reference 10894547
11782539
12432063
12502791
12874278
15192701
7980435
12393899
12610628
12808104
2164470
LocusLink ID 98033
84027
66806
2932
56493
56637
78144
FunctionalClass kinase
protein binding
protein kinase
protein serine/threonine kinase
tau-protein kinase
glycogen synthase kinase 3
nucleotide binding
transferase
ATP binding
cAMP-dependent protein kinase
protein kinase CK2
beta-catenin binding
RGD ID 70982
Hugo Symbol GSK3B
Unigene ID Hs.282359
Mm.200770
Rn.10426
Hs.445733
GO Cellular Component cytosol
nucleus
cytoplasm
Cell Localization Cytoplasm
Nucleus
Pathway Insulin Receptor Signaling
Wnt signaling
NOTCH1 -> TCF3 signalling pathway
NOTCH1 -> CTNNB1 signalling pathway
NOTCH2 -> TCF3 signalling pathway
NOTCH4 -> HEY1 signalling pathway
NOTCH4 -> HEY2 signalling pathway
NTRK1 -> MYCN signalling pathway
TEK -> TCF3 signalling pathway
TGFBR1 -> MYC signalling pathway
TRIO -> MYC signalling pathway
ADRB1 -> MYC signalling pathway
TNFRSF6 -> MYC signalling pathway
IGF1R -> MYC signalling pathway
IGF1R -> MYCN signalling pathway
ITGB1 -> MYC signalling pathway
KIT -> MYC signalling pathway
CCKBR -> CTNNB1 signalling pathway
CD2 -> MYC signalling pathway
CD4 -> NFATC2 signalling pathway
CD4 -> MADH3 signalling pathway
CD28 -> MYC signalling pathway
CD38 -> MYBL1 signalling pathway
CD79A -> MYC signalling pathway
EPHA4 -> CTNNB1 signalling pathway
ERBB2 -> CTNNB1 signalling pathway
F2R -> CTNNB1 signalling pathway
FSHR -> GATA4 signalling pathway
SPN -> MYC signalling pathway
GCGR -> TP53 signalling pathway
PDGFRB -> MYC signalling pathway
CSF1R -> MYC signalling pathway
CSF3R -> MYC signalling pathway
BDNF-NCAM1
BDNF-NGFR
BDNF-NTRK1
BDNF-NTRK2
BDNF-NTRK3
DKK1-LRP6
EGF-EGFR
EGF-ERBB2
EGF-ERBB3
EGF-ERBB4
EGF-LRP8
EGF-NGFR
EPO-EPOR
FGF1-FGFR1
FGF1-FGFR2
FGF1-FGFR3
FGF1-GPC1
FGF2-CD44
FGF2-FGFR1
FGF2-FGFR2
FGF2-FGFR3
FGF2-GPC1
FGF2-TGFBR3
GH1-GHR
GH1-IGF1R
GH1-PRLR
HGF-CD44
HGF-FGFR2
HGF-IL6R
HGF-MET
IGF1-BST1
IGF1-IGF1R
IGF1-IGF2R
IGF1-LRP5
IGF2-IGF1R
IGF2-IGF2R
IL6-IL6R
IL6-IL6ST
IL6-LIFR
IL6-TNFRSF5
IL7-IL2RG
IL7-IL7R
INS-EGFR
INS-HLA-DRB1
INS-IGF1R
INS-TFRC
KITLG-KIT
LEP-LEPR
LEP-LRP2
NGFB-NGFR
NGFB-NTRK1
NGFB-NTRK2
NGFB-NTRK3
TGFB1-ACVR1
TGFB1-ACVR1B
TGFB1-ACVR2
TGFB1-ACVR2B
TGFB1-ACVRL1
TGFB1-BMPR1B
TGFB1-CD44
TGFB1-IGF2R
TGFB1-IL6R
TGFB1-M6PR
TGFB1-SELE
TGFB1-SELL
TGFB1-TGFBR1
TGFB1-TGFBR2
TGFB1-TGFBR3
THPO-EPOR
THPO-MPL
TNF-IL15RA
TNF-NGFR
TNF-TNFRSF1A
TNF-TNFRSF1B
TNF-TNFRSF6
TNFSF10-TNFRSF10A
TNFSF10-TNFRSF10B
TNFSF10-TNFRSF1A
TNFSF10-TNFRSF6
WNT1-LRP5
WNT1-LRP6
WNT1-ROR2
CB0480 Insulin
GO Biological Process Wnt receptor signaling pathway
glycogen metabolism
protein amino acid phosphorylation
anti-apoptosis
cell proliferation
fat cell differentiation
organogenesis
protein-nucleus export
re-entry into mitotic cell cycle
response to stress
establishment and/or maintenance of cell polarity
establishment of cell polarity
induction of apoptosis
negative regulation of transcription, DNA-dependent
adipocyte differentiation
Group Kinases
EC Number 2.7.1.37
MGI ID 1861437
Swiss-Prot Accession P49841
OMIM ID OMIM:605004
605004
Source Curated
 
Change Country | Contact Us | Privacy Policy | Terms and Conditions
 
©2008 Calbiochem, Novabiochem, & Novagen
are brands of EMD Chemicals Inc., an Affiliate of Merck KGaA, Darmstadt, Germany.