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Hydroxylapatite
 | | | | Hydroxylapatite (HA), a modified form of crystalline calcium phosphate, is an extremely useful chromatomedium for purification and fractionation of a variety of biological substances, including proteins and nucleic acids. HA does not adsorb amino acids, small peptides or dyestuffs, making it an eminently advantageous material for protein purification. HA chromatography has been extensively utilized in enzyme purification, fractionation of antigens from serum proteins, separation of b-lipoproteins and g-globulins, and for separation and purification of nucleic acids. Two different adsorbing sites have been described on the HA crystal surface, a calcium site that binds with the acidic groups, and a phosphate site that interacts with the basic protein groups. The adsorption of proteins and nucleic acids does not cause any detectable change in their physical, chemical or biological properties. | | |
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| Hydroxylapatite, Fast Flow |
White solid |
391947 |
| Hydroxylapatite, High Resolution |
White solid |
391948 |
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