CSCKDMTDKECLYFCHQDVIW
SRTX-b Lyophilized. Sold on the basis of peptide content. PROTECT FROM MOISTURE. Endothelin-related peptide that binds to the endothelin receptor in various tissues (Kd = 150 pM). Increases intracellular Ca2+ levels by activating ETA receptors. Exhibits vasoconstrictor activity and stimulates protein synthesis. Purity: ≥97% by HPLC. Sold on the basis of peptide content. CAS 116303-65-2. H-Cys1-Ser-Cys3-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys11-Leu-Tyr-Phe-Cys15-His-Gln-Asp-Val-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11) Ref.: Bacon, C.R., and Davenport, A.P. 1996. Br. J. Pharmacol. 117, 986. Bax, W.A., et al. 1994. Br. J. Pharmacol. 113, 1471. Koyama, Y., et al. 1993. Brain Res. 600, 81. Sugden, P.H., et al. 1993. Biochim. Biophys. Acta 1175, 327. Watanabe, C., et al. 1993. Br. J. Pharmacol. 108, 30. Marsault, R., et al. 1991. Am. J. Physiol. 261, C987.
R: 20/21/22; S: 36 |
