Liquid. In 150 mM NaCl, 50 mM Tris-HCl, pH 7.5. AVOID FREEZE/THAW CYCLES. Recombinant, human 14-3-3g fused to GST at the N-terminus with a thrombin cleavage site and expressed in E. coli. Useful for protein-protein interaction assays and gel overlays. The 14-3-3 protein family consists of a group of highly conserved proteins that may regulate the function of signal transduction complexes by modulating their enzymatic activity, conformation, stability, and/or intracellular localization. 14-3-3g is an adapter protein involved in the regulation of a large spectrum of signaling pathways. Purity: ≥90% by SDS-PAGE. Ref.: Autieri, M.V. 2004. Exp. Mol. Pathology 76, 99. Yaffe, M.B., et al. 2002. FEBS Lett. 513, 53. Furlantetto, R.W., et al. 1997. Biochem. J. 327, 765. |