N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide, HCl Off-white solid. HYGROSCOPIC. A shorter alkyl chain derivative of W-7 that inhibits casein kinase I (Ki = 80 µM), casein kinase II (Ki = 5.1 µM), myosin light chain kinase (Ki = 7.4 µM), protein kinase A (Ki = 4.3 µM), protein kinase C (Ki = 47 µM), and protein kinase G (Ki = 3.8 µM). Purity: ≥98% by TLC. Ref.: Inagaki, M., et al. 1986. Mol. Pharmacol. 29, 577. Turner, E.J.H., et al. 2003. Br. J. Haematol. 120, 894. |
