ACV Acycloguanosine 9-(2-Hydroxyethoxy)methylguanine White solid. An antiviral nucleoside analog. Inhibits the proliferation of NIH 3T3 fibroblastic cells transformed by either v-abl or bcr-abl. Synchronizes OM9:22 leukemia cells at the G0/G1 phase of the cell cycle. Purity: ≥98% by HPLC. RTECS UP0791400, CAS 59277-89-3. Merck Index: 14, 146 Ref.: Nishimaki, J., et al. 1996. Leuk. Res. 20, 415. Cioé, L., et al. 1992. J. Biol. Chem. 267, 22178. Whitley, R.J., and Gnann, J.W., Jr. 1992. N. Engl. J. Med. 327, 782. |