Adamantane-acetyl-(6-aminohexanoyl)3-(leucinyl)3-vinyl-(methyl)-sulfone Off-white powder. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A potent, covalent, cell-permeable, irreversible inhibitor of chymotrypsin-like (50-100 nM), trypsin-like (1-5 µM), and PGPH (0.5-1 µM) activities of the 20S proteasome. Purity: ≥90% by HPLC. Ref.: Kessler, B.M., et al. 2001. Chem. Biol. 8, 913. |
