A-3:5-MP cAMP, Na White solid. HYGROSCOPIC. A key regulator of many cellular reactions. Released in response to hormonal stimulation. An activator of protein kinase A. Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Acts as a second messenger in signal transduction mechanisms. Promotes apoptosis in resting human B lymphocytes. Purity: ≥98% by HPLC. RTECS AU7357900, CAS 37839-81-9. Merck Index: 14, 2708 Ref.: Kawasaki, H., et al. 1998. Science 282, 2275. de Rooij, J., et al. 1998. Nature 396, 474. Lomo, J., et al. 1995. J. Immunol. 154, 1634. |