8-CPT-cAMP, Na

White solid. HYGROSCOPIC. Cell-permeable cAMP analog that activates both protein kinase A and protein kinase G. Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Also acts as a potent inhibitor of cGMP-specific phosphodiesterase (IC₅₀ = 900 nM). Inhibits cAMP-specific phosphodiesterase at much higher concentrations (IC₅₀ = 25 µM). Purity: ≥98% by HPLC. CAS 93882-12-3.

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