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SID: 26758148

GSK-3 Signaling Interactive Pathway
  Adenosine 3′,5′-cyclic Monophosphorothioate, Sp-Isomer, Triethylammonium Salt
Cat. No. 116815  
All Categories » Calbiochem » Biochemicals » Activators » Kinase » Protein Kinase A

Adenosine 3′,5′-cyclic Phosphorothioate-Sp
Sp-cAMPS, TEA

Crystalline solid. HYGROSCOPIC. A cell-permeable cAMP analog that binds cAMP-receptor proteins. Induces the guanine-nucleotide exchange factor activity of GEFI (also known as Epac) and GEFII towards Raf1, both in vivo and in vitro. Known to cause a decrease in cytosolic pH. Note: 10 µmol = 4.47 mg. Purity: ≥98% by HPLC. CAS 71774-13-5. Note: 10 µmol = 4.47 mg.

Ref.: Kawasaki, H., et al. 1998. Science 282, 2275. de Rooij, J., et al. 1998. Nature 396, 474. Kaji, H., et al. 1992. Biochem. Biophys. Res. Commun. 182, 1356. Sugimoto, T., et al. 1992. J. Cell Physiol. 152, 28. Van Der Kloot, W., and Branisteanu, D.D. 1992. Pflugers Arch. 420, 336. Takuma, T., and Ichida, T. 1991. J. Biochem. 110, 292. Dostmann, W.R., et al. 1990. J. Biol. Chem. 265, 10484.
Sold under license of Patent DE 3,802,865.4 issued to BIOLOG LSI.

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10 µmolYN/A

SolubilityMolecular FormulaMol. Wt.
H2C10H11N5O5PS · (CH3CH2)3NH 446.5 


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116815: Adenosine 3′,5′-cyclic Monophosphorothioate, Sp-Isomer, Triethylammonium Salt - English
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Related Categories:
All Categories » Calbiochem » Biochemicals » Activators » Kinase » Protein Kinase A