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SID: 26758149

Inhibitor Resource

GSK-3 Signaling Interactive Pathway

Inhibitor Database
  Adenosine 3′,5′-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt
Cat. No. 116816  
All Categories » Calbiochem » Inhibitors » Kinase and Phosphatase » Protein Kinase A (PKA)

Rp-8-Br-cAMPS, Na

Lyophilized. HYGROSCOPIC. A potent, cell-permeable, metabolically-stable cAMP antagonist that inhibits cAMP-dependent protein kinase and shows preference for PKA type I. More lipophilic than cAMP antagonist Rp-cAMPS (Cat. No. 116814). Purity: ≥99% by HPLC. Note: 5 µmol = 2.23 mg.

Ref.: Calaghan, S.C., et al. 1999. Pflugers Arch. 437, 780. Gjertsen, B.T., et al. 1995. J. Biol. Chem. 270, 20599. Yokozaki, H., et al. 1992. Cancer Res. 52, 2504. Dostmann, W.R. et al. 1990. J. Biol. Chem. 265, 10484.
Sold under license of Patent DE 3,802,865.4 issued to BIOLOG LSI.

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EMD Chemicals Inc. USD list price is displayed (pricing with local distributors may vary). NOTE: In Stock status is based on item availability worldwide.

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5 µmolY$486.00


SolubilityMolecular FormulaMol. Wt.
H2C10H10BrN5O5PS · Na 446.1 


Related Literature:

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Second Messengers Brochure

Inhibitor Sourcebook

Material Safety Data Sheets:
116816: Adenosine 3′,5′-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - English
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Related Categories:
All Categories » Calbiochem » Inhibitors » Kinase and Phosphatase » Protein Kinase A (PKA)

Selected Citations:
  1. Ralf Gutzmer, et al. (2005) Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells. Journal of Immunology 5224-5232.