Rp-8-Br-cAMPS, Na Lyophilized. HYGROSCOPIC. A potent, cell-permeable, metabolically-stable cAMP antagonist that inhibits cAMP-dependent protein kinase and shows preference for PKA type I. More lipophilic than cAMP antagonist Rp-cAMPS (Cat. No. 116814). Purity: ≥99% by HPLC. Note: 5 µmol = 2.23 mg. Ref.: Calaghan, S.C., et al. 1999. Pflugers Arch. 437, 780. Gjertsen, B.T., et al. 1995. J. Biol. Chem. 270, 20599. Yokozaki, H., et al. 1992. Cancer Res. 52, 2504. Dostmann, W.R. et al. 1990. J. Biol. Chem. 265, 10484. Sold under license of Patent DE 3,802,865.4 issued to BIOLOG LSI. |