Rp-MB-cAMPS, Na Lyophilized. HYGROSCOPIC. A cell-permeable, metabolically-stable precursor of Rp-cAMPS (Cat. No. 116814) that acts as a competitive inhibitor of protein kinase A type I and II. During metabolic activation by esterases, the inhibitor and butyrate are released. Reported to inhibit glucose-induced proliferation of the pancreatic b-cell line, INS-1. More lipophilic and cell-permeable than Rp-cAMPS. Purity: ≥98% by HPLC. CAS 152218-23-0. Note: 5 µmol = 2.19 mg. Ref.: Vischer, U.M., and Wollheim, C.B. 1998. Blood 91, 118.
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