Adenosine 5′-triphosphate, P3-1-(2-Nitrophenyl)ethyl Ester, 2Na Off-white solid. PROTECT FROM LIGHT. HYGROSCOPIC. Photolabile derivative of ATP that selectively releases ATP upon irradiation with short pulses of light of about 360 nm, allowing time and dose-dependent jumps in ATP concentration. Physiological responses resulting from the release of ATP can be studied over a shorter time frame (milliseconds) than was previously possible. Caged ATP has been used to study the effects of ATP on the relaxation of muscle fibers eliminating the limitation of time resolution inherent to the diffusion technique. 1 set = 10 x 500 µg. Purity: >90% by HPLC. Extinction coefficient(260 nm, H2O): 19,000 M-1cm-1. CAS 125229-58-5. Note: 1 set = 10 x 500 µg. Ref.: Somlyo, A.V., et al. 1992. J. Biol. Chem. 267, 22316. Tanner, J.W., et al. 1992. J. Mol. Biol. 223, 185. Chang, C.H., et al. 1990. Eur. J. Pharmacol. 189, 111. Hibberd, M.G., and Trentham, D.R. 1986. Annu. Rev. Biophys. Chem. 15, 119. |
