7-n-Butyl-6-(4-methoxyphenyl)[5H]pyrrolo[2,3-b]pyrazine
RP106 Cream-colored solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A cell-permeable pyrrolo-pyrazine compound that exerts anti-proliferative effects. Acts as a potent, selective, ATP-competitive inhibitor of CDK1/cyclin B, CDK5/p25, and GSK-3 (IC50 = 700 nM, 1.5 µM, and 920 nM, respectively). Purity: ≥95% by HPLC. CAS 496864-15-4. Ref.: Mettey, Y., et al. 2003. J. Med. Chem. 46, 222. |
