Off-white solid. HYGROSCOPIC. A cell-permeable potent inhibitor of inducible nitric oxide synthase (iNOS) activity in murine macrophages (IC50 = 68 µM) and rat aortic smooth muscle cells in culture. Purity: ≥95% by elemental analysis. Ref.: Wolff, D.J., et al. 1997. J. Pharmacol. Exp. Ther. 283, 265. Ruetten, H., et al. 1996. Br. J. Pharmacol. 118, 261. |