3-Aminobenzamide White solid. A cell-permeable anti-proliferative agent that acts as an inhibitor of poly(ADP-ribose) polymerase (PARP). Has minimal effect on bacterial toxin-mediated ADP-ribosylation. An inhibitor of UV-induced apoptosis. Also strongly inhibits K562 target cell killing by human effector natural killer cells. Purity: ≥97% by TLC. RTECS CU8992000, CAS 3544-24-9. Ref.: Tiozzo, R., et al. 1996. Biochem. Biophys. Res. Commun. 225, 826. Malorni, W., et al. 1995. Biochem. Biophys. Res. Commun. 207, 715. Malorni, W., et al. 1994. Biochem. Biophys. Res. Commun. 199, 1250. Monti, D., et al. 1994. Biochem. Biophys. Res. Commun. 199, 525. Kozak, K.R., and Ross, I.A. 1991. Biochem. Biophys. Res. Commun. 179, 1225. R: 36/37/38; S: 26-36 |