Fungizone

Yellow solid. PROTECT FROM LIGHT. A polyene antifungal antibiotic that non-specifically induces loss of low molecular weight substances from cells. Binds to sterols and disrupts osmotic integrity of fungal membrane. Causes suppression of bone marrow progenitor cells. Purity: >86% by HPLC. RTECS BU2625000, CAS 1397-89-3.

Merck Index: 14, 585
Ref.: Tollemar, J., et al. 1995. Transplantation 59, 45. Charak, B.S., et al. 1994. Br. J. Haematol. 88, 693. Barth, C., et al. 1993. J. Biophys. 64, 92.
R: 20/21-36/37/38; S: 26-36