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MAPK Interactive Pathway™
  Anandamide
Cat. No. 172100  
All Categories » Calbiochem » Biochemicals » Lipids » Fatty Acids and Derivatives

Arachidonylethanolamide

Yellow oil. PROTECT FROM LIGHT. PROTECT FROM MOISTURE. PACKAGED UNDER INERT GAS. An arachidonic acid derivative and a potential ligand for the cannabinoid receptor. Inhibits the specific binding of a radiolabeled cannabinoid probe, HU-243 (Ki = 52 nM). This inhibition is not reversed by the addition of the opioid antagonist naloxane. Also inhibits Ca2+ currents in N18 neuroblastoma cells, inhibits lymphocyte proliferation, and induces apoptosis. Stimulates MAP kinase activity in hematopoietic cell lines. Purity: ≥97% by HPLC. RTECS JX3842500, CAS 94421-68-8.

Ref.: Derocq, J.M., et al. 1998. FEBS Lett. 425, 419. Wartmann, M., et al. 1995. FEBS Lett. 359, 133. Schwarz, H., et al. 1994. Neuroimmunology 55, 107. Johnson, D.E., et al. 1993. Prostag. Leuko. Essential Fatty Acids 48, 429. Mackie, K., et al. 1993. Soc. Neurosci. 19, Abstract 722.4. Barinaga, M., et al. 1992. Science 258, 1882. Devane, W.A., et al. 1992. Science 258, 1946. Pertwee, R.G., et al. 1992. Br. J. Pharmacol. 105, 980.

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SolubilityMolecular FormulaMol. Wt.
EtOH or DMSO C22H37NO2 347.5 


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172100: Anandamide - English
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All Categories » Calbiochem » Biochemicals » Lipids » Fatty Acids and Derivatives