(Ala9)-Autocamtide-2
AIP
KKALRRQEAVDAL White solid. Supplied as a trifluoroacetate salt. HYGROSCOPIC. Non-phosphorylatable analog of Autocamtide-2 (Cat. No. 189475) that acts as a highly specific and potent inhibitor of calmodulin-dependent protein kinase II (IC50 = 40 nM). It is about 50 times more potent than [Ala286]-CaM kinase II Inhibitor, 281-301 (Cat. No. 208710). Has no effect on PKA, PKC, and CaM kinase IV. Blocks Ca2+-induced insulin secretion from electropermeabilized islets. Purity: ≥97% by HPLC. H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH Ref.: Bhat, H.S., et al. 2000. Biochem. Pharmacol. 60, 1655. Ishida, A., et al. 1995. Biochem. Biophys. Res. Commun. 212, 806. | 
