Tan solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A Kenpaullone (Cat. No. 422000) analog that acts as a potent and ATP-competitive inhibitor of GSK-3b (IC50 = 18 nM), and displays ~100-200 fold greater selectivity over Cdk1/B and Cdk5/p25 (IC50 = 2 µM and 4.2 µM, respectively). Purity: ≥95% by HPLC. CAS 676596-65-9. Ref.: Kunick, C., et al. 2004. Bioorg. Med. Chem. Lett. 14, 413. |
