Altracin Gray-white solid. A polypeptide antibiotic and peptidase inhibitor. An inhibitor of protein disulfide isomerase. Resembles penicillin in causing protoplast formation and inhibition of cell wall synthesis. Blocks the regeneration of carrier phospholipid. Stimulates 5-hydroxytryptamine receptors and increases vascular resistance. Biological activity: Potency ≥40 Bacitracin units/mg solid, as is. One unit is defined as the amount of antibiotic equal to 26 µg of the USP standard. Note: 1 ku = 1000 units. RTECS CP0175000, CAS 1405-87-4. Note: 1 KU = 1000 units. Merck Index: 14, 934
Ref.: Ikai, Y., et al. 1995. J. Antibiot. (Tokyo) 48, 233. Clive, D.R., et al. 1994. Exp. Cell Res. 214, 139. |
