Anti-b-Site Amyloid Precursor Protein (APP)-Cleaving Enzyme Anti-b-Secretase | Host: Rabbit | | Isotype: IgG | | Immunogen: a synthetic peptide [ETDEEPEEPGRRGSFVEMVD(C)] corresponding to amino acids 46-65 of human BACE | | Form: Liquid | | Formulation: Undiluted serum. | | Preservative: None | | Comments: Recognizes the ~65 and the ~75 kDa glycosylated forms of BACE in CHO cells transfected with BACE. Recognizes the ~50 kDa deglycosylated BACE after treatment with endoglycosidase F. | | Ref.: Pinnix, I., et al. 2001. FASEB J. 15, 1810. Bennett, B.D., et al. 2000. J. Biol. Chem. 275, 37712. Capell, A., et al. 2000. J. Biol. Chem. 275, 30849. Lin X., et al. 2000. Proc. Natl. Acad. Sci. USA 97, 1456. Vassar, R., et al. 1999. Science 286, 735. Yan, R., et al. 1999. Nature 402, 533. | |