Ant-BH3-A78 H-RQIKIWFQNRRMKWKKMGQVGRQAAIIGDDINRRY-OH Off-white lyophilized solid. Supplied as a trifluoroacetate salt. HYGROSCOPIC. PACKAGED UNDER INERT GAS. A cell-permeable, Antennapedia-BH3 (Bcl-2 homology 3 domain from Bak) mutated (Leu78 replaced by Ala) fusion peptide analog of Ant-BH3 (Cat. No. 196350) that may be useful as a negative control. Shown to be defective in binding to Bcl-xL. Has little to no apoptotic effect. Purity: ≥95% by HPLC. H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Met-Gly-Gln-Val-Gly-Arg-Gln-Ala-Ala-Ile-Ile-Gly-Asp-Asp-Ile-Asn-Arg-Arg-Tyr-OH Ref.: Holinger, E.P., et al. 1999. J. Biol. Chem. 274, 13298. |