[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu White crystalline solid. Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has antitumor properties. Purity: >99% by titration (dry basis). RTECS OH2915000, CAS 58970-76-6. Merck Index: 14, 9842
Ref.: Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171. Taylor, A., et al. 1993. Biochemistry 32, 784. Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381. Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75. |
