N′-(1-(3-Chloro-4-fluorophenyl)-4-cyano-1H-pyrazol-5-yl)-N,N-dimethyliminoformamide Brown solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A cell-permeable pyrazolo compound that inhibits cytokinesis function of the Aurora B kinase pathway. Inhibits Histone H3 phosphorylation on Ser10 in mitotic Drosophila Kc167 cells at 20 µM, while inactive in mammalian systems. Does neither function as a general kinase inhibitor nor inhibit Cdk-dependent entry into mitosis. Purity: ≥95% by HPLC. CAS 220088-42-6. Ref.: Eggert, U.S., et al. 2004. PLoS Biol. 2, 2135. | 
