2-[1-[2-(1-Methylpyrrolidino)ethyl]-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide Orange solid. A potent, cell permeable, and selective inhibitor of protein kinase C (IC50 = 13 nM). May inhibit protein kinase A at much higher concentrations (IC50 = 2 µM). Purity: ≥95% by HPLC. Ref.: Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771. Sold under license of U.S. Patent 5,380,746. |