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  InSolution™ Bisindolylmaleimide I
Cat. No. 203293  
All Categories » Calbiochem » Inhibitors » Kinase and Phosphatase » Protein Kinase C (PKC)

2-[1-(3-Dimethylaminopropyl)-1H-indol-3-yl]-3-(1H-indol-3-yl)-maleimide
Gö 6850

Liquid. A 1 mg/ml solution of Bisindolylmaleimide I (Cat. No. 203290) in anhydrous DMSO. PACKAGED UNDER INERT GAS. Purity: ≥95% by HPLC. CAS 133052-90-1.

Ref.: Ku, W.-C., et al. 1997. Biochem. Biophys. Res. Commun. 241, 730. Gekeler, V., et al. 1996. Br. J. Cancer 74, 897. Kiss, Z., et al. 1995. Biochim. Biophys. Acta 1265, 93. Muid, R.E., et al. 1991. FEBS Lett. 293, 160. Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771.
R: 36/38; S: 26
Sold under license of U.S. Patent 5,380,746.

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1 mlYN/A

SolubilityMolecular FormulaMol. Wt.
 C25H24N4O2 412.5 


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203293: InSolution™ Bisindolylmaleimide I - English
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All Categories » Calbiochem » Inhibitors » Kinase and Phosphatase » Protein Kinase C (PKC)

Selected Citations:
  1. Alexandra Thiel, Mira Heinonen, Johanna Rintahaka, Tuija Hallikainen, and Annabrita Hemmes, Dan A. Dixon, Caj Haglund, and Ari Ristimaki. (2006) EXPRESSION OF CYCLOOXYGENASE-2 IS REGULATED BY GSK-3 IN GASTRIC CANCER CELLS. Journal of Biological Chemistry in press,.
  2. Xiaohua Jiang, et al. (2005) Hyperhomocystinemia impairs endothelial function and eNOS activity via PKC activation. Arteriosclerosis, Thrombosis, and Vascular Biology in press,.
  3. Ademi E. Santiago-Walker, et al. (2005) Protein Kinase C δ Stimulates Apoptosis by Initiating G1 Phase Cell Cycle Progression and S Phase Arrest. Journal of Biological Chemistry 280, 32107-32114.
  4. Wojciech Wojciechowski, et al. (2005) Enhanced Expression of CD20 in Human Tumor B Cells is Controlled Through ERK-Dependent Mechanisms. Journal of Immunology 174, 7859-7868.