Arcyriarubin A
2,3-bis(1H-Indol-3-yl)maleimide Orange solid. A potent, cell permeable, and selective inhibitor of protein kinase C (IC50 = 87 nM). Inhibits protein kinase A at much higher concentrations (IC50 = 2.7 µM). Purity: ≥95% by HPLC. CAS 119139-23-0. Ref.: Fabre, S., et al. 1993. Bioorg. Med. Chem. 1, 193. Davis, P.D., et al. 1992. J. Med. Chem. 35, 177. Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771. |
