2,3-bis(1H-Indol-3-yl)-N-methylmaleimide
Ro 31-6045 Redish orange solid. A cell-permeable negative control compound for protein kinase C inhibition studies (IC50 >100 µM). Blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k in vivo (IC50 8 µM). Purity: ≥95% by HPLC. CAS 113963-68-1. Ref.: Marmy-Conus, N., et al. 2002. FEBS Lett. 26094 (In Press) 1-6. Davis, P.D., et al. 1992. J. Med. Chem. 35, 177. Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771. |
