White solid. HYGROSCOPIC. Nucleoside antibiotic that specifically inhibits protein synthesis in both prokaryotes and eukaryotes. Suitable for use as a dominant selectable marker in conjunction with blasticidin S resistant plasmids. Blasticidin S resistance is conferred by the blasticidin S deaminase gene (bcr), which converts blastisidin S to a nontoxic deaminohydroxy derivative. Purity: ≥ 98% by HPLC. CAS 3513-03-9. Merck Index: 14, 1316 Ref.: Kimura, M., et al. 1994. Biochim. Biophys. Acta 1219, 653. Kimura, M., et al. 1994, Mol. Gen. Genet. 242, 121. Kojima, N., et al. 1994. J. Biol. Chem. 269, 30451. Kudo, T., et al. 1994. J. Immunol. Methods 177, 17. Sutoh, K. 1993. Plasmid 30, 150. Izumi, M., et al. 1991. Exp. Cell Res. 197, 229. Yamaguchi, H., et al. 1965. J. Biol. Chem. 57, 667. Takeuchi, S., et al. 1958. J. Antibiot. 11, 1. R: 28; S: 24/25-36/37-45 |