Liquid. Sterile-filtered solution supplied at 20 mg/ml in H2O. AVOID FREEZE/THAW CYCLES. A unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. BLEOCIN™ Antibiotic cleaves double-stranded DNA and inhibits DNA synthesis, resulting in cell death. Can be used for selection of recombinant clones in a variety of cell types transfected with vectors containing a ble resistance marker. RTECS EC5990700, CAS 55658-47-4. Merck Index: 14, 1318
Ref.: Sergeev, D.S., et al. 1995. Bioorg. Khim. 21, 695. Mulsant, P., et al. 1988. Somat. Cell Mol. Genet. 14, 243. Ehrenfeld, G.M., et al. 1987. Biochemistry 26, 931. Takita, T., et al. 1972. J. Antibiot. 25, 755. |
