[6-Benzylamino-2-(3-hydroxypropylamino)-9-isopropylpurine White solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A synthetic, cell-permeable, cyclin-dependent kinase (CDK) inhibitor (IC50 = 1 µM) that is structurally similar to Olomoucine (Cat. No. 495620) and Roscovitine (Cat. No. 557360). Arrests cell cycle in the G1/S boundary and activates in vitro matured bovine oocytes either alone or in combination with Ionomycin (Cat. Nos. 407950 and 407952). Purity: ≥95% by HPLC. CAS 189232-42-6. Ref.: Chmela, Z., et al. 2001. Drug Metab. Dispos. 29, 326. Alberio, R., et al. 2000. Mol. Reprod. Dev. 55, 422. Binarova, P., et al. 1998. Plant J. 16, 697. |
