H-Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 White to off-white lyophilized solid. HYGROSCOPIC. A tetradecapeptide that activates a cascade of biochemical reactions including Ins(1,4,5)P3-induced mobilization of intracellular Ca2+, protein kinase C activation, Na+,and K+ fluxes, and cAMP production. Potent mitogen of Swiss/3T3 cells. Stimulates phospholipase D in Swiss/3T3 fibroblasts. Purity: ≥97% by HPLC. Sold on the basis of peptide content. RTECS BD3480000, CAS 31362-50-2. H-Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 (Pyr = 5-oxoPro) Merck Index: 14, 1329
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