Potassium Bisperoxo(bipyridine)oxovanadate (V) Yellow to orange solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A potent inhibitor of phosphotyrosine phosphatase (Ki = 100 nM for insulin receptor dephosphorylation). An activator of insulin receptor kinase (IRK). Also reported to be a potent inhibitor of PTEN (IC50 = 18 nM). Purity: ≥95% by 51V-NMR. Ref.: Schmid, A.C., et al. 2004. FEBS Lett. 566, 35. Posner, B.I., et al. 1994. J. Biol. Chem. 269, 4596. R: 20/21/22; S: 36 |