Dipotassium Bisperoxo(5-hydroxypyridine-2-carboxyl)oxovanadate (V) Yellow solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A potent phosphotyrosine phosphatase inhibitor. Activates the insulin receptor kinase (IRK) of hepatoma cells. Also stimulates lipogenesis in isolated adipocytes. Also reported to potently inhibit PTEN (IC50 = 14 nM). Purity: ≥80% by 51V-NMR. Ref.: Schmid, A.C., et al. 2004. FEBS Lett. 566, 35. Posner, B.I., et al. 1994. J. Biol. Chem. 269, 4596. |