Calbiochem: 203800: Adenosine 3′,5′-cyclic Monophosphate, 8-Bromo-, Sodium Salt

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��	Adenosine 3′,5′-cyclic Monophosphate, 8-Bromo-, Sodium Salt

Cat. No. 203800��

All Categories � Calbiochem � Biochemicals � Activators � Kinase � Protein Kinase A

8-Bromo-cAMP, Na

White solid. HYGROSCOPIC. Cell-permeable cAMP analog that has greater resistance to phosphodiesterases than cAMP. Preferentially activates protein kinase A (PKA). Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Purity: ≥98% by HPLC. CAS 76939-46-3.

Ref.: Kawasaki, H., et al. 1998. Science 282, 2275. de Rooij, J., et al. 1998. Nature 396, 474. Boyer, B., and Thiery, J.P. 1993. J. Cell Biol. 120, 767. Hei, Y.-J., et al. 1991. Mol. Pharmacol. 39, 233.

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Solubility	Molecular Formula	Mol. Wt.
H₂O�	C₁₀H₁₀BrN₅O₆P � Na�	430.1�

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203800: Adenosine 3′,5′-cyclic Monophosphate, 8-Bromo-, Sodium Salt - English
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Related Categories:
All Categories � Calbiochem � Biochemicals � Activators � Kinase � Protein Kinase A

Selected Citations:
Michael J. Cross, et al. (2002) The Shb Adaptor Protein Binds to Tyrosine 766 in the FGFR-1 and Regulates the Ras/MEK/MAPK Pathway via FRS2 Phosphorylation in Endothelial Cells. Molecular Biology of the Cell 13, 2881-2893.

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