PBN White solid. Most commonly-used free radical trap. An antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative disorders. Inhibits lipid peroxidation in rat liver microsomes. Also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species. Purity: ≥98% by GC. CAS 3376-24-7. Ref.: Floyd, R.A. 1997. Adv. Pharmacol. 38, 361. Miyajima, T., and Kotake, Y. 1995. Biochem. Biophys. Res. Commun. 215, 114. Jazen, E.G., et al. 1994. in Frontiers of Reactive Oxygen Species in Biology and Medicine, (Asada, K., and Yoshikawa, T., eds.), pp. 431-434. Elsevier Science, Amsterdam. Floyd, R.A. 1990. FASEB J. 4, 2587. |
