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  CA-074 Me
Cat. No. 205531  
All Categories » Calbiochem » Inhibitors » Protease » Cathepsin

Cathepsin B Inhibitor IV
[L-3-trans-(Propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline Methyl Ester

White solid. A cell-permeable analog of CA-074 (Cat. No. 205530) that acts as an irreversible inhibitor of intracellular cathepsin B. Reported to inhibit bone resorption in rodent models and shown to inhibit B16 melanoma cell invasion in vitro. Purity: ≥98% by HPLC.

Ref.: Sever, N., et al. 2002. Biol. Chem. 383, 839. Authier, F., et al. 1999. J. Biol. Chem. 274, 33723. Hill, P.A., et al. 1994. J. Cell Biochem. 56, 118. Buttle, D.J., et al. 1992. Arch. Biochem. Biophys. 299, 377.

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1 mgY$168.00


SolubilityMolecular FormulaMol. Wt.
DMSO C19H31N3O6 397.5 


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205531: CA-074 Me - English
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All Categories » Calbiochem » Inhibitors » Protease » Cathepsin