3,4-Dihydroxycinnamic Acid Tan crystalline solid. PACKAGED UNDER INERT GAS. A natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties. A cell-permeable, selective, non-competitive inhibitor of 5-lipoxygenase (ID50 = 3.7 µM). Inhibits Cu2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase. Purity: ≥95% by HPLC. RTECS GD8950000, CAS 331-39-5. Merck Index: 14, 1635
Ref.: Yamanaka, N., et al. 1997. FEBS Lett. 405, 186. Chan, W.S., et al. 1995. Anticancer Res. 15, 703. Ploemen, J.H., et al. 1993. Food Chem. Toxicol. 31, 475. Koshihara, Y., et al. 1984. Biochim. Biophys. Acta 792, 92.
R: 40; S: 36/37 |
