White lyophilized solid. Domain I of human calpastatin. Endogenous protease inhibitor that acts specifically on Calpain-1 (Cat. No. 208712). Exhibits greater inhibitory potency than calpain inhibitors I and II. Biological activity: 50 nM completely inhibits the activity of 7.5 µg/ml calpain I. Purity: homogeneous by SDS-PAGE. Ref.: Salamino, F., et al. 1994. Biochem. Biophys. Res. Commun. 199, 1326. Uemori, T., et al. 1990. Biochem. Biophys. Res. Commun. 166, 1485. Asada, K., et al. 1989. J. Enzyme Inhib. 3, 49.
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